Sleep: A Health Imperative
UPMC Health System · University of Pittsburgh · +3 more institutions
Abstract
Chronic sleep deficiency, defined as a state of inadequate or mistimed sleep, is a growing and underappreciated determinant of health status. Sleep deprivation contributes to a number of molecular, immune, and neural changes that play a role in disease development, independent of primary sleep disorders. These changes in biological processes in response to chronic sleep deficiency may serve as etiological factors for the development and exacerbation of cardiovascular and metabolic diseases and, ultimately, a shortened lifespan. Sleep deprivation also results in significant impairments in cognitive and motor performance which increase the risk of motor vehicle crashes and work-related injuries and fatal…
Citation impact
- FWCI
- 31.77
- Percentile
- 100%
- References
- 109
Authors
4Topics & keywords
- Sleep (system call)
- Sleep deprivation
- Medicine
- Sleep medicine
- Disease
- Sleep debt
- Exacerbation
- Gerontology