articleNucleic Acids ResearchDec 18, 2003BRONZE OA

SCOP database in 2004: refinements integrate structure and sequence family data

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Abstract

The Structural Classification of Proteins (SCOP) database is a comprehensive ordering of all proteins of known structure, according to their evolutionary and structural relationships. Protein domains in SCOP are hierarchically classified into families, superfamilies, folds and classes. The continual accumulation of sequence and structural data allows more rigorous analysis and provides important information for understanding the protein world and its evolutionary repertoire. SCOP participates in a project that aims to rationalize and integrate the data on proteins held in several sequence and structure databases. As part of this project, starting with release 1.63, we have initiated a refinement of the SCOP…

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Topics & keywords

Keywords
  • Structural Classification of Proteins database
  • Biology
  • Sequence (biology)
  • Protein family
  • Set (abstract data type)
  • Domain (mathematical analysis)
  • Database
  • Computational biology
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