Markers of Inflammation, Coagulation, and Renal Function Are Elevated in Adults with HIV Infection
University of Minnesota · University of Minnesota System · +11 more institutions
Abstract
Human immunodeficiency virus (HIV) replication and immune activation may increase inflammation and coagulation biomarkers. Limited data exist comparing such biomarkers in persons with and without HIV infection.
For persons 45-76 years of age, levels of high-sensitivity C-reactive protein (hsCRP), interleukin (IL)-6, D-dimer, and cystatin C were compared in 494 HIV-infected individuals in the Strategies for Management of Anti-Retroviral Therapy (SMART) study and 5386 participants in the Multi-Ethnic Study of Atherosclerosis (MESA) study. For persons 33-44 years of age, hsCRP and IL-6 levels were compared in 287 participants in the SMART study and 3231 participants in the Coronary Artery Development in Young Adults (CARDIA) study.
Citation impact
- FWCI
- 53.63
- Percentile
- 100%
- References
- 37
Authors
13- JNJacqueline NeuhausCorresponding
University of Minnesota
- DRDavid R. Jacobs
University of Minnesota, University of Minnesota System
- JVJason V. Baker
University of Minnesota System, Hennepin County Medical Center
- ACAlexandra Calmy
University of Geneva, University Hospital of Geneva
- DDDaniel Duprez
University of Minnesota System, University of Minnesota
Topics & keywords
- Human immunodeficiency virus (HIV)
- Immunology
- Inflammation
- Coagulation
- Renal function
- Medicine
- Internal medicine
- Good health and well-being