PubChem: a public information system for analyzing bioactivities of small molecules
National Center for Biotechnology Information · National Institutes of Health
Abstract
PubChem (http://pubchem.ncbi.nlm.nih.gov) is a public repository for biological properties of small molecules hosted by the US National Institutes of Health (NIH). PubChem BioAssay database currently contains biological test results for more than 700 000 compounds. The goal of PubChem is to make this information easily accessible to biomedical researchers. In this work, we present a set of web servers to facilitate and optimize the utility of biological activity information within PubChem. These web-based services provide tools for rapid data retrieval, integration and comparison of biological screening results, exploratory structure-activity analysis, and target selectivity examination. This article reviews…
Citation impact
- FWCI
- 79.40
- Percentile
- 100%
- References
- 15
Authors
6- YWY. WangCorresponding
National Center for Biotechnology Information, National Institutes of Health
- JXJ. Xiao
National Center for Biotechnology Information, National Institutes of Health
- TÖTuğba Önal-Süzek
National Center for Biotechnology Information, National Institutes of Health
- JZJian Zhang
National Institutes of Health, National Center for Biotechnology Information
- JWJiguang Wang
National Institutes of Health, National Center for Biotechnology Information
Topics & keywords
- PubChem
- Bioassay
- Computer science
- Biology
- World Wide Web
- Computational biology