articleBMC BioinformaticsNov 24, 2014GOLD OA

ANGSD: Analysis of Next Generation Sequencing Data

Natural History Museum of Denmark · Natural History Museum Aarhus · +2 more institutions

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Abstract

Background

High-throughput DNA sequencing technologies are generating vast amounts of data. Fast, flexible and memory efficient implementations are needed in order to facilitate analyses of thousands of samples simultaneously.

Results

We present a multithreaded program suite called ANGSD. This program can calculate various summary statistics, and perform association mapping and population genetic analyses utilizing the full information in next generation sequencing data by working directly on the raw sequencing data or by using genotype likelihoods.

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Funding