articleGutJan 9, 2009BRONZE OA

Magnetic resonance for assessment of disease activity and severity in ileocolonic Crohn’s disease

Centro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas · Hospital Clínic de Barcelona · +2 more institutions

PubMed
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Abstract

Objective

Assessment of disease extension and activity is crucial to guide treatment in Crohn's disease. The objective of the current cross-sectional study was to determine the accuracy of MR for this assessment.

Design

50 patients with clinically active (n = 35) or inactive (n = 15) Crohn's disease underwent ileocolonoscopy (reference standard) and MR. T2-weighted and precontrast and postcontrast-enhanced T1-weighted sequences were acquired. Endoscopic activity was evaluated by CDEIS (Crohn's Disease Endoscopic Index of Severity); in addition endoscopic lesions were classified as absent, mild (inflammation without ulcers) or severe (presence of ulceration).

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