articleHepatologyDec 11, 2007BRONZE OA

Diagnosis of hepatic nodules 20 mm or smaller in cirrhosis: Prospective validation of the noninvasive diagnostic criteria for hepatocellular carcinoma

AFAlejandro FornerRVR. VilanaCACarmen AyusoLBLluís BianchiMSManel Solé

Centro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas · Consorci Institut D'Investigacions Biomediques August Pi I Sunyer · +5 more institutions

PubMed
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Abstract

This study prospectively evaluates the accuracy of contrast-enhanced ultrasound (CEUS) and dynamic magnetic resonance imaging (MRI) for the diagnosis of nodules 20 mm or smaller detected during ultrasound (US) surveillance. We included 89 patients with cirrhosis [median age, 65 years; male 53, hepatitis C virus 68, Child-Pugh A 80] without prior hepatocellular carcinoma (HCC) in whom US detected a small solitary nodule (mean diameter, 14 mm). Hepatic MRI, CEUS, and fine-needle biopsy (gold standard) (FNB) were performed at baseline. Non-HCC cases were followed (median 23 months) by CEUS/3 months and MRI/6 months. FNB was repeated up to 3 times and on detection of change in aspect/size. Intense arterial…

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Topics & keywords

Topics
Keywords
  • Medicine
  • Hepatocellular carcinoma
  • Cirrhosis
  • Focal nodular hyperplasia
  • Biopsy
  • Ultrasound
  • Radiology
  • Contrast-enhanced ultrasound
UN Sustainable Development Goals
  • Good health and well-being
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