articleGeneticsMar 18, 2009GREEN OA

Predicting Quantitative Traits With Regression Models for Dense Molecular Markers and Pedigree

Institut Pasteur de Montevideo · University of Wisconsin–Madison · +1 more institution

PubMed
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Abstract

The availability of genomewide dense markers brings opportunities and challenges to breeding programs. An important question concerns the ways in which dense markers and pedigrees, together with phenotypic records, should be used to arrive at predictions of genetic values for complex traits. If a large number of markers are included in a regression model, marker-specific shrinkage of regression coefficients may be needed. For this reason, the Bayesian least absolute shrinkage and selection operator (LASSO) (BL) appears to be an interesting approach for fitting marker effects in a regression model. This article adapts the BL to arrive at a regression model where markers, pedigrees, and covariates other than…

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619
total citations
FWCI
21.58
Percentile
100%
References
25
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Authors

8

Topics & keywords

Keywords
  • Pedigree chart
  • Lasso (programming language)
  • Regression
  • Covariate
  • Biology
  • Regression analysis
  • Bayesian probability
  • Selection (genetic algorithm)
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