The chemistry and engineering of polymeric hydrogel adhesives for wound closure: a tutorial

The closure and repair of wounds after traumatic or surgical injury is of significant clinical and research importance. While sutures remain the common wound closure technique, they have many disadvantages. Consequently, polymeric hydrogel adhesives have emerged as essential materials for wound management and repair because of their tunable chemical and physical properties, which enable them to adhere or stick to tissues, possess sufficient mechanical strength to stay intact and be subsequently removed, provide complete wound occlusion, and act as a barrier to bacterial infection. Moreover, these materials absorb wound exudates and keep the wound moist for faster healing. This tutorial review summarizes the…

• WH
  Wallace H. Coulter Foundation
• NI
  National Institutes of Health

  Awards: R01EY13881, R21 EB013721