A method for normalizing histology slides for quantitative analysis
North Carolina State University · University of North Carolina at Chapel Hill · +3 more institutions
Abstract
Inconsistencies in the preparation of histology slides make it difficult to perform quantitative analysis on their results. In this paper we provide two mechanisms for overcoming many of the known inconsistencies in the staining process, thereby bringing slides that were processed or stored under very different conditions into a common, normalized space to enable improved quantitative analysis.
Citation impact
- FWCI
- 4.55
- Percentile
- 100%
- References
- 12
Authors
8- MMMarc MacenkoCorresponding
North Carolina State University, University of North Carolina at Chapel Hill
- MNMarc Niethammer
North Carolina State University, University of North Carolina at Chapel Hill
- JSJ. S. Marron
University of North Carolina at Chapel Hill, University of North Carolina at Asheville
- DBDavid Borland
Renaissance Computing Institute, University of North Carolina at Chapel Hill, North Carolina State University
- JTJohn T. Woosley
University of North Carolina at Chapel Hill, North Carolina State University
Topics & keywords
- Computer science
- Process (computing)
- Quantitative analysis (chemistry)
- Artificial intelligence
- Chromatography
- Chemistry