Early versus Delayed Invasive Intervention in Acute Coronary Syndromes
Population Health Research Institute · Hamilton Health Sciences · +13 more institutions
Abstract
Earlier trials have shown that a routine invasive strategy improves outcomes in patients with acute coronary syndromes without ST-segment elevation. However, the optimal timing of such intervention remains uncertain.
We randomly assigned 3031 patients with acute coronary syndromes to undergo either routine early intervention (coronary angiography or = 36 hours after randomization). The primary outcome was a composite of death, myocardial infarction, or stroke at 6 months. A prespecified secondary outcome was death, myocardial infarction, or refractory ischemia at 6 months.
Citation impact
- FWCI
- 43.55
- Percentile
- 100%
- References
- 32
Authors
18- SRShamir R. MehtaCorresponding
Population Health Research Institute, Hamilton Health Sciences, McMaster University
- CBChristopher B. Granger
Clinical Research Institute
- WEWilliam E. Boden
University at Buffalo, State University of New York
- PGPhilippe Gabríel Steg
Inserm, Université Paris Cité, Assistance Publique – Hôpitaux de Paris
- JBJean‐Pierre Bassand
Centre Hospitalier Universitaire de Besançon
Topics & keywords
- Medicine
- Acute coronary syndrome
- Percutaneous coronary intervention
- Intervention (counseling)
- Intensive care medicine
- Cardiology
- Internal medicine
- Myocardial infarction
- Good health and well-being