articleMolecular Biology and EvolutionMay 4, 2011BRONZE OA

MEGA5: Molecular Evolutionary Genetics Analysis Using Maximum Likelihood, Evolutionary Distance, and Maximum Parsimony Methods

KTKoichiro TamuraDGDaniel G. PetersonNPNora PetersonGSGlen StecherMNM Nei

Arizona State University · Tokyo Metropolitan University · +1 more institution

PubMed
Indexed incrossrefdoajpubmed

Abstract

Comparative analysis of molecular sequence data is essential for reconstructing the evolutionary histories of species and inferring the nature and extent of selective forces shaping the evolution of genes and species. Here, we announce the release of Molecular Evolutionary Genetics Analysis version 5 (MEGA5), which is a user-friendly software for mining online databases, building sequence alignments and phylogenetic trees, and using methods of evolutionary bioinformatics in basic biology, biomedicine, and evolution. The newest addition in MEGA5 is a collection of maximum likelihood (ML) analyses for inferring evolutionary trees, selecting best-fit substitution models (nucleotide or amino acid), inferring…

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Topics & keywords

Topics
Keywords
  • Phylogenetic tree
  • Biology
  • Maximum parsimony
  • Mega-
  • Phylogenetics
  • Tree (set theory)
  • Evolutionary biology
  • Molecular evolution
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