articleBrainSep 22, 2009BRONZE OA

Updated clinical diagnostic criteria for sporadic Creutzfeldt-Jakob disease

University of Göttingen · Western General Hospital · +21 more institutions

PubMed
Indexed incrossrefdatacitepubmed

Abstract

Several molecular subtypes of sporadic Creutzfeldt-Jakob disease have been identified and electroencephalogram and cerebrospinal fluid biomarkers have been reported to support clinical diagnosis but with variable utility according to subtype. In recent years, a series of publications have demonstrated a potentially important role for magnetic resonance imaging in the pre-mortem diagnosis of sporadic Creutzfeldt-Jakob disease. Magnetic resonance imaging signal alterations correlate with distinct sporadic Creutzfeldt-Jakob disease molecular subtypes and thus might contribute to the earlier identification of the whole spectrum of sporadic Creutzfeldt-Jakob disease cases. This multi-centre international study…

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918
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100%
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Authors

27

Topics & keywords

Keywords
  • Magnetic resonance imaging
  • Differential diagnosis
  • Putamen
  • Medicine
  • Pathology
  • Disease
  • Cerebrospinal fluid
  • Dementia
UN Sustainable Development Goals
  • Partnerships for the goals
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