articleBioinformaticsJan 1, 2002BRONZE OA

Tumor classification by partial least squares using microarray gene expression data

University of California System · University of California, Davis · +1 more institution

PubMed
Indexed incrossrefdoajpubmed

Abstract

MOTIVATION: One important application of gene expression microarray data is classification of samples into categories, such as the type of tumor. The use of microarrays allows simultaneous monitoring of thousands of genes expressions per sample. This ability to measure gene expression en masse has resulted in data with the number of variables p(genes) far exceeding the number of samples N. Standard statistical methodologies in classification and prediction do not work well or even at all when N

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Authors

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Topics & keywords

Keywords
  • Microarray analysis techniques
  • Linear discriminant analysis
  • Dimensionality reduction
  • Principal component analysis
  • Microarray
  • Chronic lymphocytic leukemia
  • Partial least squares regression
  • Mathematics
UN Sustainable Development Goals
  • Reduced inequalities
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