articleNucleic Acids ResearchNov 21, 2014GOLD OA

DIANA-TarBase v7.0: indexing more than half a million experimentally supported miRNA:mRNA interactions

National and Kapodistrian University of Athens · University of Thessaly · +2 more institutions

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Abstract

MicroRNAs (miRNAs) are short non-coding RNA species, which act as potent gene expression regulators. Accurate identification of miRNA targets is crucial to understanding their function. Currently, hundreds of thousands of miRNA:gene interactions have been experimentally identified. However, this wealth of information is fragmented and hidden in thousands of manuscripts and raw next-generation sequencing data sets. DIANA-TarBase was initially released in 2006 and it was the first database aiming to catalog published experimentally validated miRNA:gene interactions. DIANA-TarBase v7.0 (http://www.microrna.gr/tarbase) aims to provide for the first time hundreds of thousands of high-quality manually curated…

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