The bHLH Transcription Factor POPEYE Regulates Response to Iron Deficiency in Arabidopsis Roots
Duke University · Center for Systems Biology · +1 more institution
Abstract
Global population increases and climate change underscore the need for better comprehension of how plants acquire and process nutrients such as iron. Using cell type-specific transcriptional profiling, we identified a pericycle-specific iron deficiency response and a bHLH transcription factor, POPEYE (PYE), that may play an important role in this response. Functional analysis of PYE suggests that it positively regulates growth and development under iron-deficient conditions. Chromatin immunoprecipitation-on-chip analysis and transcriptional profiling reveal that PYE helps maintain iron homeostasis by regulating the expression of known iron homeostasis genes and other genes involved in transcription,…
Citation impact
- FWCI
- 36.44
- Percentile
- 100%
- References
- 66
Authors
6Topics & keywords
- Transcription factor
- Biology
- Chromatin immunoprecipitation
- Arabidopsis
- Ubiquitin ligase
- Cell biology
- Transcription (linguistics)
- Promoter
- Climate action