articleProceedings of the National Academy of SciencesApr 2, 2002Closed access

Mapping the evolution of regional atrophy in Alzheimer's disease: Unbiased analysis of fluid-registered serial MRI

UK Dementia Research Institute · National Hospital for Neurology and Neurosurgery · +1 more institution

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Abstract

Alzheimer's disease (AD) is characterized by progressive cerebral atrophy, which may be assessed by using volumetric MRI. We describe a voxel-based analysis of nonlinear-registered serial MRI to demonstrate the most statistically significant (P

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