articleBioinformaticsFeb 1, 2002BRONZE OA

Generating samples under a Wright–Fisher neutral model of genetic variation

University of Chicago

PubMed
Indexed incrossrefdoajpubmed

Abstract

Abstract Summary: A Monte Carlo computer program is available to generate samples drawn from a population evolving according to a Wright–Fisher neutral model. The program assumes an infinite-sites model of mutation, and allows recombination, gene conversion, symmetric migration among subpopulations, and a variety of demographic histories. The samples produced can be used to investigate the sampling properties of any sample statistic under these neutral models. Availability: The source code for the program (in the language C) is available at http://home.uchicago.edu/~rhudson1/source/mksamples.html. Contact: rr-hudson@uchicago.edu

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Authors

1

Topics & keywords

Keywords
  • Wright
  • Statistic
  • Monte Carlo method
  • Sampling (signal processing)
  • Statistics
  • Variation (astronomy)
  • Population
  • Sample (material)
UN Sustainable Development Goals
  • Reduced inequalities
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