reviewAnnual Review of NeuroscienceMar 1, 2003Closed access

C ELL M IGRATION IN THE F OREBRAIN

Consejo Superior de Investigaciones Científicas · Instituto de Neurociencias · +2 more institutions

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Abstract

The forebrain comprises an intricate set of structures that are required for some of the most complex and evolved functions of the mammalian brain. As a reflection of its complexity, cell migration in the forebrain is extremely elaborated, with widespread dispersion of cells across multiple functionally distinct areas. Two general modes of migration are distinguished in the forebrain: radial migration, which establishes the general cytoarchitectonical framework of the different forebrain subdivisions; and tangential migration, which increases the cellular complexity of forebrain circuits by allowing the dispersion of multiple neuronal types. Here, we review the cellular and molecular mechanisms underlying each…

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