Coronary microvascular dysfunction: an update

Many patients undergoing coronary angiography because of chest pain syndromes, believed to be indicative of obstructive atherosclerosis of the epicardial coronary arteries, are found to have normal angiograms. In the past two decades, a number of studies have reported that abnormalities in the function and structure of the coronary microcirculation may occur in patients without obstructive atherosclerosis, but with risk factors or with myocardial diseases as well as in patients with obstructive atherosclerosis; furthermore, coronary microvascular dysfunction (CMD) can be iatrogenic. In some instances, CMD represents an epiphenomenon, whereas in others it is an important marker of risk or may even contribute to…

• DK
  Deutsches Krebsforschungszentrum
• SF
  Society for Women’s Health Research
• LH
  Ladies Hospital Aid Society
• CM
  Cedars-Sinai Medical Center
• Q
  Qmed
• NI
  National Institutes of Health

  Awards: N01-HV-68163, U01 HL649241, MO1-RR00425, N01-HV-68161, N01-HV-68162, U01 HL649141, N01-HV-68164, RR00425, UL1TR000124, R01 HL090957
• NC
  National Center for Advancing Translational Sciences

  Award: UL1TR000124