Learning the Languages of the Chloroplast: Retrograde Signaling and Beyond

The chloroplast can act as an environmental sensor, communicating with the cell during biogenesis and operation to change the expression of thousands of proteins. This process, termed retrograde signaling, regulates expression in response to developmental cues and stresses that affect photosynthesis and yield. Recent advances have identified many signals and pathways-including carotenoid derivatives, isoprenes, phosphoadenosines, tetrapyrroles, and heme, together with reactive oxygen species and proteins-that build a communication network to regulate gene expression, RNA turnover, and splicing. However, retrograde signaling pathways have been viewed largely as a means of bilateral communication between…

• CS
  Commonwealth Scientific and Industrial Research Organisation
• UB
  Universität Bielefeld
• CO
  Centre of Excellence in Plant Energy Biology, Australian Research Council

  Award: CE140100008
• UO
  University of California, Davis