Highly evolvable malaria vectors: The genomes of 16 Anopheles mosquitoes
Broad Institute · University of Geneva · +62 more institutions
Abstract
INTRODUCTION Control of mosquito vectors has historically proven to be an effective means of eliminating malaria. Human malaria is transmitted only by mosquitoes in the genus Anopheles , but not all species within the genus, or even all members of each vector species, are efficient malaria vectors. Variation in vectorial capacity for human malaria among Anopheles mosquito species is determined by many factors, including behavior, immunity, and life history. RATIONALE This variation in vectorial capacity suggests an underlying genetic/genomic plasticity that results in variation of key traits determining vectorial capacity within the genus. Sequencing the genome of Anopheles gambiae , the most important malaria…
Citation impact
- FWCI
- 25.29
- Percentile
- 100%
- References
- 249
Authors
120- DEDaniel E. NeafseyCorresponding
Broad Institute
- RMRobert M. Waterhouse
University of Geneva, Vassar College, SIB Swiss Institute of Bioinformatics, Massachusetts Institute of Technology
- MRMohammad Reza Abai
Tehran University of Medical Sciences
- SASergey Aganezov
George Washington University Virginia Campus
- MAMax A. Alekseyev
George Washington University Virginia Campus
Topics & keywords
- Biology
- Genome
- Anopheles
- Evolutionary biology
- Gene
- Malaria
- Vector (molecular biology)
- Genetics
- Life in Land