Characterization of freezing of gait subtypes and the response of each to levodopa in Parkinson's disease
Tel Aviv University · Tel Aviv Sourasky Medical Center · +2 more institutions
Abstract
To assess the effect of levodopa on distinct freezing of gait (FOG) subtypes in patients with 'off' FOG. Nineteen patients (12 men, mean age 62.0 +/- 8.4 years) with Parkinson's disease and clinically significant FOG during 'off' states were videotaped whilst walking 130 m during 'off' and 'on' states. Three independent observers characterized the type, duration, and clinical manifestations and quantified FOG by analyzing the videotapes. Their combined mean scores were used for statistical analysis. The intra-class correlation coefficient assessed inter-observer reliability. Wilcoxon and Friedman tests evaluated differences in mean frequencies of FOG characteristics. During 'off' states, FOG was elicited by…
Citation impact
- FWCI
- 3.48
- Percentile
- 100%
- References
- 35
Authors
6- JDJoanna D. SchaafsmaCorresponding
Tel Aviv University, Tel Aviv Sourasky Medical Center
- YBYacov Balash
Tel Aviv University, Tel Aviv Sourasky Medical Center
- TGTanya Gurevich
Tel Aviv University, Tel Aviv Sourasky Medical Center
- ALAnna L. Bartels
Tel Aviv University, Tel Aviv Sourasky Medical Center
- JMJeffrey M. Hausdorff
Beth Israel Deaconess Medical Center, Harvard University, Tel Aviv University, Tel Aviv Sourasky Medical Center
Topics & keywords
- Levodopa
- Medicine
- Parkinson's disease
- Wilcoxon signed-rank test
- Gait
- Disease
- Physical medicine and rehabilitation
- Audiology