articleJournal of Medical GeneticsMay 1, 2002BRONZE OA

Malignant peripheral nerve sheath tumours in neurofibromatosis 1

DGD. Gareth EvansMEM E BaserJMJ McGaughranSSS SharifEHE Howard

St Mary's Hospital · St. Mary's Hospital · +1 more institution

PubMed
Indexed incrossrefpubmed

Abstract

Background

Cross sectional studies have shown that 1-2% of patients with neurofibromatosis 1 (NF1) develop malignant peripheral nerve sheath tumours (MPNST). However, no population based longitudinal studies have assessed lifetime risk.

Methods

NF1 patients with MPNST were ascertained from two sources for our north west England population of 4.1 million in the 13 year period 1984-1996: the North West Regional NF1 Register and review of notes of patients with MPNST in the North West Regional Cancer Registry.

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1,269
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11.64
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100%
References
25
Citations per year

Authors

6

Topics & keywords

Keywords
  • Neurofibromatosis
  • Medicine
  • Malignant peripheral nerve sheath tumor
  • Cancer registry
  • Radiation therapy
  • Population
  • Incidence (geometry)
  • Cancer
UN Sustainable Development Goals
  • Good health and well-being
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