Breast cancer stem cell markers CD44, CD24 and ALDH1: expression distribution within intrinsic molecular subtype
Universidade do Porto · Cooperativa de Ensino Superior Politécnico e Universitário · +1 more institution
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Abstract
Methods
466 invasive breast carcinomas and eight breast cancer cell lines were analysed for the expression of CD44, CD24 and ALDH1, to evaluate their distribution among the distinct molecular subtypes.
Results
Basal-like tumours (76.5%) contained the higher percentage of cells with the CSC phenotype CD44(+)CD24(-/low) (p
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Authors
9Topics & keywords
Topics
Keywords
- CD44
- CD24
- Cancer stem cell
- Breast cancer
- Cancer research
- Cancer
- Biology
- Pathology
UN Sustainable Development Goals
- Good health and well-being
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