WOMBAT—A tool for mixed model analyses in quantitative genetics by restricted maximum likelihood (REML)
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Abstract
WOMBAT is a software package for quantitative genetic analyses of continuous traits, fitting a linear, mixed model; estimates of covariance components and the resulting genetic parameters are obtained by restricted maximum likelihood. A wide range of models, comprising numerous traits, multiple fixed and random effects, selected genetic covariance structures, random regression models and reduced rank estimation are accommodated. WOMBAT employs up-to-date numerical and computational methods. Together with the use of efficient compilers, this generates fast executable programs, suitable for large scale analyses. Use of WOMBAT is illustrated for a bivariate analysis. The package consists of the executable…
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Topics
Keywords
- Restricted maximum likelihood
- Executable
- Mixed model
- Bivariate analysis
- Generalized linear mixed model
- Computer science
- Covariance
- Covariate
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