articleJournal of Zhejiang University SCIENCE BOct 1, 2007HYBRID OA

WOMBAT—A tool for mixed model analyses in quantitative genetics by restricted maximum likelihood (REML)

University of New England

PubMed
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Abstract

WOMBAT is a software package for quantitative genetic analyses of continuous traits, fitting a linear, mixed model; estimates of covariance components and the resulting genetic parameters are obtained by restricted maximum likelihood. A wide range of models, comprising numerous traits, multiple fixed and random effects, selected genetic covariance structures, random regression models and reduced rank estimation are accommodated. WOMBAT employs up-to-date numerical and computational methods. Together with the use of efficient compilers, this generates fast executable programs, suitable for large scale analyses. Use of WOMBAT is illustrated for a bivariate analysis. The package consists of the executable…

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Authors

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Topics & keywords

Keywords
  • Restricted maximum likelihood
  • Executable
  • Mixed model
  • Bivariate analysis
  • Generalized linear mixed model
  • Computer science
  • Covariance
  • Covariate
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