articleNeurologyFeb 16, 2011BRONZE OA

Classification of primary progressive aphasia and its variants

MGMaria‐Luisa Gorno‐TempiniAEArgye E. HillisSWSandra WeıntraubAKAndrew KerteszMFMario F. Mendez

University of Trento · Mayo Clinic · +1 more institution

PubMed
Indexed incrossrefpubmed

Abstract

This article provides a classification of primary progressive aphasia (PPA) and its 3 main variants to improve the uniformity of case reporting and the reliability of research results. Criteria for the 3 variants of PPA--nonfluent/agrammatic, semantic, and logopenic--were developed by an international group of PPA investigators who convened on 3 occasions to operationalize earlier published clinical descriptions for PPA subtypes. Patients are first diagnosed with PPA and are then divided into clinical variants based on specific speech and language features characteristic of each subtype. Classification can then be further specified as "imaging-supported" if the expected pattern of atrophy is found and "with…

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Topics & keywords

Topics
Keywords
  • Primary progressive aphasia
  • Consistency (knowledge bases)
  • Operationalization
  • Natural language processing
  • Computer science
  • Reliability (semiconductor)
  • Aphasia
  • Medicine
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