MYB58 and MYB63 Are Transcriptional Activators of the Lignin Biosynthetic Pathway during Secondary Cell Wall Formation in Arabidopsis   

It has previously been shown that SECONDARY WALL-ASSOCIATED NAC DOMAIN PROTEIN1 (SND1) is a key transcription factor regulating secondary cell wall formation, including the biosynthesis of cellulose, xylan, and lignin. In this study, we show that two closely related SND1-regulated MYB transcription factors, MYB58 and MYB63, are transcriptional regulators specifically activating lignin biosynthetic genes during secondary wall formation in Arabidopsis thaliana. MYB58 and MYB63 are phylogenetically distinct from previously characterized MYBs shown to be associated with secondary wall formation or phenylpropanoid metabolism. Expression studies showed that MYB58 and MYB63 are specifically expressed in fibers and…

• NS
  National Science Foundation

  Award: 0744170
• UD
  U.S. Department of Energy

  Awards: DE-FG02-03ER15415, FG02-03ER15415, DE-FG02-, DE-FG02
• OO
  Office of Science
• BE
  Basic Energy Sciences

  Awards: DE-FG02, DE-FG02-03ER15415
• CS
  Chemical Sciences, Geosciences, and Biosciences Division