articleStrokeJun 17, 2005Closed access

Safety and Efficacy of Mechanical Embolectomy in Acute Ischemic Stroke

University of Southern California · Hartford Hospital · +8 more institutions

PubMed
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Abstract

Methods

We investigated the safety and efficacy of a novel embolectomy device (Merci Retriever) to open occluded intracranial large vessels within 8 hours of the onset of stroke symptoms in a prospective, nonrandomized, multicenter trial. All patients were ineligible for intravenous tPA. Primary outcomes were recanalization and safety, and secondary outcomes were neurological outcome at 90 days in recanalized versus nonrecanalized patients.

Results

Recanalization was achieved in 46% (69/151) of patients on intention to treat analysis, and in 48% (68/141) of patients in whom the device was deployed. This rate is significantly higher than that expected using an historical control of 18% (P

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1,314
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References
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Citations per year

Authors

14

Topics & keywords

Keywords
  • Medicine
  • Embolectomy
  • Stroke (engine)
  • Ischemic stroke
  • Cardiology
  • Brain ischemia
  • Ischemia
  • Internal medicine
UN Sustainable Development Goals
  • Good health and well-being
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Funding