Clinical Relevance of Biomarkers of Oxidative Stress

SIGNIFICANCE: Oxidative stress is considered to be an important component of various diseases. A vast number of methods have been developed and used in virtually all diseases to measure the extent and nature of oxidative stress, ranging from oxidation of DNA to proteins, lipids, and free amino acids. RECENT ADVANCES: An increased understanding of the biology behind diseases and redox biology has led to more specific and sensitive tools to measure oxidative stress markers, which are very diverse and sometimes very low in abundance. CRITICAL ISSUES: The literature is very heterogeneous. It is often difficult to draw general conclusions on the significance of oxidative stress biomarkers, as only in a limited…

• TF
  Toyota Foundation
• EC
  European Cooperation in Science and Technology

  Awards: BM1203/EU-ROS, BM1203
• NI
  National Institutes of Health

  Award: HL116263
• DS
  Defence Science and Technology Laboratory
• MR
  Medical Research Council
• NH
  National Health and Medical Research Council

  Award: 1060804
• ER
  European Regional Development Fund
• DS
  Defence Science and Technology Group
• I
  Interreg