articleEuropean Heart JournalMar 6, 2013BRONZE OA

Incidence and epidemiology of new onset heart failure with preserved vs. reduced ejection fraction in a community-based cohort: 11-year follow-up of PREVEND

FPFrank P. BrouwersRARudolf A. de BoerPVPim van der HarstAAAdriaan A. VoorsRTRon T. Gansevoort

University Medical Center Groningen · University of Groningen

PubMed
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Abstract

AIMS: Differences in clinical characteristics and outcome of patients with established heart failure with preserved ejection fraction (HFpEF) and heart failure with reduced ejection fraction (HFrEF) are well established. Data on epidemiology and prediction of new onset HFpEF, compared with HFrEF, have not been described. METHODS AND RESULTS: In 8592 subjects of the Prevention of Renal and Vascular End-stage Disease (PREVEND), a community-based, middle-aged cohort study, we performed cause-specific hazard analyses to study the predictive value of risk factors and established cardiovascular biomarkers on new onset HFrEF vs. HFpEF (left ventricular ejection fraction ≤ 40 and ≥ 50%, respectively). A P-value for…

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Topics & keywords

Topics
Keywords
  • Medicine
  • Internal medicine
  • Cardiology
  • Heart failure
  • Ejection fraction
  • Hazard ratio
  • Heart failure with preserved ejection fraction
  • Cohort
UN Sustainable Development Goals
  • Good health and well-being
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