reviewNew England Journal of MedicineOct 5, 2011Closed access

Filaggrin Mutations Associated with Skin and Allergic Diseases

ADAlan D. IrvineWIW.H. Irwin McLeanDYDonald Y.M. Leung

Trinity College · National Jewish Health · +1 more institution

PubMed
Indexed incrossrefpubmed

Abstract

Mutations in the filaggrin gene are associated with a broad range of skin and allergic diseases. The biology of this molecule and the role of mutations in its altered function offer new insights into a range of conditions not previously thought to be related to one another.

Citation impact

1,198
total citations
FWCI
85.54
Percentile
100%
References
99
Citations per year

Authors

3

Topics & keywords

Topics
Keywords
  • Filaggrin
  • Mutation
  • Genetics
  • Biology
  • Atopic dermatitis
  • Medicine
  • Gene
  • Immunology
UN Sustainable Development Goals
  • Good health and well-being
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