reviewBiopolymersJan 1, 2010Closed access

Self‐assembly of peptide amphiphiles: From molecules to nanostructures to biomaterials

Northwestern University · Evanston Hospital

PubMed
Indexed incrossrefpubmed

Abstract

Abstract Peptide amphiphiles are a class of molecules that combine the structural features of amphiphilic surfactants with the functions of bioactive peptides and are known to assemble into a variety of nanostructures. A specific type of peptide amphiphiles are known to self‐assemble into one‐dimensional nanostructures under physiological conditions, predominantly nanofibers with a cylindrical geometry. The resultant nanostructures could be highly bioactive and are of great interest in many biomedical applications, including tissue engineering, regenerative medicine, and drug delivery. In this context, we highlight our strategies for using molecular self‐assembly as a toolbox to produce peptide amphiphile…

Citation impact

1,524
total citations
FWCI
45.46
Percentile
100%
References
73
Citations per year

Authors

3

Topics & keywords

Keywords
  • Amphiphile
  • Nanotechnology
  • Chemistry
  • Context (archaeology)
  • Nanostructure
  • Nanofiber
  • Peptide
  • Drug delivery
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