articleNeuroImageNov 11, 2015HYBRID OA

Bayesian model reduction and empirical Bayes for group (DCM) studies

Wellcome Centre for Human Neuroimaging · University College London · +5 more institutions

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Abstract

This technical note describes some Bayesian procedures for the analysis of group studies that use nonlinear models at the first (within-subject) level - e.g., dynamic causal models - and linear models at subsequent (between-subject) levels. Its focus is on using Bayesian model reduction to finesse the inversion of multiple models of a single dataset or a single (hierarchical or empirical Bayes) model of multiple datasets. These applications of Bayesian model reduction allow one to consider parametric random effects and make inferences about group effects very efficiently (in a few seconds). We provide the relatively straightforward theoretical background to these procedures and illustrate their application…

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