reviewCanadian Medical Association JournalMay 14, 2012GOLD OA

The prognosis of acute and persistent low-back pain: a meta-analysis

LDLuciola da C. Menezes CostaCGChristopher G. MaherMJMark J. HancockJHJames H. McAuleyRHRob Herbert

The University of Sydney · The George Institute for Global Health · +5 more institutions

PubMed
Indexed incrossrefdoajpubmed

Abstract

Background

Although low-back pain is a highly prevalent condition, its clinical course remains uncertain. Our main objective was to systematically review the literature on the clinical course of pain and disability in patients with acute and persistent low-back pain. Our secondary objective was to investigate whether pain and disability have similar courses.

Methods

We performed a meta-analysis of inception cohort studies. We identified eligible studies by searching MEDLINE, Embase and CINAHL. We included prospective studies that enrolled an episode-inception cohort of patients with acute or persistent low-back pain and that measured pain, disability or recovery. Two independent reviewers extracted data and assessed methodologic quality. We used mixed models to determine pooled estimates of pain and disability over time.

Citation impact

642
total citations
FWCI
22.58
Percentile
100%
References
60
Citations per year

Authors

6

Topics & keywords

Topics
Keywords
  • Medicine
  • Meta-analysis
  • Cohort study
  • Back pain
  • Prospective cohort study
  • CINAHL
  • MEDLINE
  • Physical therapy
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Funding