Highly Enantioselective Conjugate Addition of Nitromethane to Chalcones Using Bifunctional Cinchona Organocatalysts

Vakulya, Benedek; Varga, Szilárd; Csámpai, Antal; Soós, Tibor

doi:10.1021/ol050431s

articleOrganic LettersApr 14, 2005Closed access

Highly Enantioselective Conjugate Addition of Nitromethane to Chalcones Using Bifunctional Cinchona Organocatalysts

BVBenedek Vakulya SVSzilárd VargaACAntal CsámpaiTSTibor Soós

Hungarian Academy of Sciences · Eötvös Loránd University

PubMed

Indexed incrossrefpubmed

Abstract

Cinchona alkaloid-derived chiral bifunctional thiourea organocatalysts were synthesized and applied in the Michael addition between nitromethane and chalcones with high ee and chemical yields.

Citation impact

978

total citations

FWCI: 26.32
Percentile: 100%
References: 11

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Authors

4

BV
Benedek VakulyaCorresponding
Hungarian Academy of Sciences, Eötvös Loránd University
SV
Szilárd Varga
Eötvös Loránd University, Hungarian Academy of Sciences
AC
Antal Csámpai
Hungarian Academy of Sciences, Eötvös Loránd University
TS
Tibor Soós
Hungarian Academy of Sciences, Eötvös Loránd University

Topics & keywords

Topics

Keywords

Nitromethane
Chemistry
Enantioselective synthesis
Bifunctional
Cinchona
Conjugate
Cinchona Alkaloids
Organocatalysis

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