COT drives resistance to RAF inhibition through MAP kinase pathway reactivation
Broad Institute · Massachusetts Institute of Technology · +5 more institutions
Indexed incrossrefpubmed
Abstract
No abstract available for this paper.
Citation impact
1,447
total citations
- FWCI
- 68.32
- Percentile
- 100%
- References
- 30
Citations per year
Authors
35- CMCory M. JohannessenCorresponding
Broad Institute, Massachusetts Institute of Technology
- JSJesse S. Boehm
Broad Institute, Massachusetts Institute of Technology
- SYSo Young Kim
Broad Institute, Genomics Institute of the Novartis Research Foundation, Harvard University, Dana-Farber Cancer Institute, Massachusetts Institute of Technology
- STSapana Thomas
Broad Institute, Harvard University, Dana-Farber Cancer Institute, Massachusetts Institute of Technology
- LWLeslie Wardwell
Harvard University, Dana-Farber Cancer Institute
Topics & keywords
Topics
Keywords
- Melanoma
- Cancer research
- Kinase
- Mutation
- Acquired resistance
- Downregulation and upregulation
- MAPK/ERK pathway
- Protein kinase A
UN Sustainable Development Goals
- Good health and well-being
No related works found for this paper.