Endothelial Progenitor Cell Dysfunction
University Medical Center Utrecht · Erasmus MC
Indexed incrossrefpubmed
Abstract
Type 1 diabetes is associated with reduced vascular repair, as indicated by impaired wound healing and reduced collateral formation in ischemia. Recently, endothelial progenitor cells (EPCs) have been identified as important regulators of these processes. We therefore explored the concept that EPCs are dysfunctional in diabetes. The number of EPCs obtained from type 1 diabetic patients in culture was 44% lower compared with age- and sex-matched control subjects (P
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837
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- 13.74
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Authors
10Topics & keywords
Topics
Keywords
- Progenitor cell
- Angiogenesis
- Endothelial progenitor cell
- Medicine
- Diabetes mellitus
- Endothelial dysfunction
- Type 2 diabetes
- Pathogenesis
UN Sustainable Development Goals
- Good health and well-being
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