The SEED and the Rapid Annotation of microbial genomes using Subsystems Technology (RAST)

In 2004, the SEED (http://pubseed.theseed.org/) was created to provide consistent and accurate genome annotations across thousands of genomes and as a platform for discovering and developing de novo annotations. The SEED is a constantly updated integration of genomic data with a genome database, web front end, API and server scripts. It is used by many scientists for predicting gene functions and discovering new pathways. In addition to being a powerful database for bioinformatics research, the SEED also houses subsystems (collections of functionally related protein families) and their derived FIGfams (protein families), which represent the core of the RAST annotation engine (http://rast.nmpdr.org/). When a…

• NS
  National Science Foundation
• UD
  U.S. Department of Energy
• NI
  National Institutes of Health
• OO
  Office of Science
• NI
  National Institute of Allergy and Infectious Diseases
• DO
  Division of Biological Infrastructure
• BA
  Biological and Environmental Research