Synchrony, Waves, and Spatial Hierarchies in the Spread of Influenza
National Institutes of Health · Pennsylvania State University · +3 more institutions
Abstract
Quantifying long-range dissemination of infectious diseases is a key issue in their dynamics and control. Here, we use influenza-related mortality data to analyze the between-state progression of interpandemic influenza in the United States over the past 30 years. Outbreaks show hierarchical spatial spread evidenced by higher pairwise synchrony between more populous states. Seasons with higher influenza mortality are associated with higher disease transmission and more rapid spread than are mild ones. The regional spread of infection correlates more closely with rates of movement of people to and from their workplaces (workflows) than with geographical distance. Workflows are described in turn by a gravity…
Citation impact
- FWCI
- 23.84
- Percentile
- 100%
- References
- 27
Authors
6- CVCécile ViboudCorresponding
National Institutes of Health, Pennsylvania State University, Center for Disease Dynamics, Economics & Policy, National Institute of Allergy and Infectious Diseases, Fogarty International Center
- ONOttar N. Bjørnstad
National Institutes of Health, Pennsylvania State University, Center for Disease Dynamics, Economics & Policy, National Institute of Allergy and Infectious Diseases, Fogarty International Center
- DLDavid L. Smith
National Institutes of Health, Pennsylvania State University, Center for Disease Dynamics, Economics & Policy, National Institute of Allergy and Infectious Diseases, Fogarty International Center
- LSLone Simonsen
National Institutes of Health, Pennsylvania State University, Center for Disease Dynamics, Economics & Policy, National Institute of Allergy and Infectious Diseases, Fogarty International Center
- MAMark A. Miller
National Institutes of Health, Pennsylvania State University, Center for Disease Dynamics, Economics & Policy, National Institute of Allergy and Infectious Diseases, Fogarty International Center
Topics & keywords
- Outbreak
- Transmissibility (structural dynamics)
- Transmission (telecommunications)
- Geography
- Pairwise comparison
- Gravity model of trade
- Range (aeronautics)
- Spatial ecology
- Good health and well-being