Frustrated Lewis Pairs

The articulation of the notion of "frustrated Lewis pairs" (FLPs), which emerged from the discovery that H2 can be reversibly activated by combinations of sterically encumbered Lewis acids and bases, has prompted a great deal of recent activity. Perhaps the most remarkable consequence has been the development of FLP catalysts for the hydrogenation of a range of organic substrates. In the past 9 years, the substrate scope has evolved from bulky polar species to include a wide range of unsaturated organic molecules. In addition, effective stereoselective metal-free hydrogenation catalysts have begun to emerge. The mechanism of this activation of H2 has been explored, and the nature and range of Lewis acid/base…

• VF
  V Foundation for Cancer Research
• AV
  Alexander von Humboldt-Stiftung
• CR
  Canada Research Chairs
• NO
  Nederlandse Organisatie voor Wetenschappelijk Onderzoek
• OM
  Ontario Ministry of Research, Innovation and Science
• UO
  University of Toronto
• NS
  Natural Sciences and Engineering Research Council of Canada
• JS
  Japan Society for the Promotion of Science