Genome-wide association study identifies loci influencing concentrations of liver enzymes in plasma

Chambers, John C.; Study, Diabetes Genetics Replication and Meta-analyses (DIAGRAM+); Zhang, Weihua; Sehmi, Joban; Li, Man; Wass, Mark N.; Harst, Pim van der; Hólm, Hilma; Sanna, Serena; Kavousi, Maryam; Baumeister, Sebastian E.; Coin, Lachlan; Deng, Guohong; Gieger, Christian; Heard‐Costa, Nancy L.; Hottenga, Jouke‐Jan; Kühnel, Brigitte; Kumar, Vinod; Lagou, Vasiliki; Liang, Liming; Luan, Jian'an; Marques‐Vidal, Pedro; Leach, Irene Mateo; O’Reilly, Paul F.; Peden, John F.; Rahmioğlu, Nilüfer; Soininen, Pasi; Speliotes, Elizabeth K.; Yuan, Xin; Þorleifsson, Guðmar; Alizadeh, Behrooz Z.; Atwood, Larry D.; Borecki, Ingrid B.; Brown, Morris J; Charoen, Pimphen; Cucca, Francesco; Das, Debashish; Geus, Eco J. C. de; Dixon, Anna; Döring, Angela; Ehret, Georg; Eyjólfsson, Guðmundur I.; Farrall, Martin; Forouhi, Nita G.; Friedrich, Nele; Goessling, Wolfram; Guðbjartsson, Daníel F.; Harris, Tamara B.; Hartikainen, Anna‐Liisa; Heath, Simon; Hirschfield, Gideon M.; Hofman, Albert; Homuth, Georg; Hyppönen, Elina; Janssen, Harry L.A.; Johnson, Toby; Kangas, Antti J.; Kema, Ido P.; Kühn, Jens‐Peter; Lai, Sandra; Lathrop, Mark; Lerch, Markus M.; Li, Yun; Liang, T. Jake; Lin, Jing‐Ping; Loos, Ruth J. F.; Martin, Nicholas G.; Moffatt, Miriam F.; Montgomery, Grant W.; Munroe, Patricia B.; Musunuru, Kiran; Nakamura, Yusuke; O’Donnell, Christopher J.; Olafsson, Isleifur; Penninx, Brenda W.J.H.; Pouta, Anneli; Prins, Bram P.; Prokopenko, Inga; Puls, Ralf; Ruokonen, Aimo; Savolainen, Markku J.; Schlessinger, David; Schouten, Jeoffrey; Seedorf, Udo; Sen‐Chowdhry, Srijita; Siminovitch, Katherine A.; Smit, Johannes H.; Spector, Timothy D; Tan, Wenting; Teslovich, Tanya M.; Tukiainen, Taru; Uitterlinden, André G.; Klauw, Melanie M. van der; Vasan, Ramachandran S.; Wallace, Chris; Wallaschofski, Henri; Wichmann, H‐Erich; Willemsen, Gonneke; Würtz, Peter; Xu, Chun; Yerges‐Armstrong, Laura M.; Abecasis, Gonçalo R.; Ahmadi, Kourosh R.; Boomsma, Dorret I; Caulfield, Mark J.; Cookson, William; Duijn, Cornelia M. van; Froguel, Philippe; Matsuda, Koichi; McCarthy, Mark I.; Meisinger, Christa; Mooser, Vincent; Pietiläinen, Kirsi H.; Schumann, Günter; Snieder, Harold; Sternberg, Michael J.E.; Stolk, Ronald P.; Thomas, Howard C.; Þorsteinsdóttir, Unnur; Uda, Manuela; Waeber, Gérard; Wareham, Nicholas J.; Waterworth, Dawn; Watkins, Hugh; Whitfield, John B.; Witteman, Jacqueline C.M.; Wolffenbuttel, Bruce H. R.; Fox, Caroline S.; Ala‐Korpela, Mika; Stefánsson, Kāri; Vollenweider, Péter; Völzke, Henry; Schadt, Eric E.; Scott, James; Järvelin, Marjo‐Riitta; Elliott, Paul; Kooner, Jaspal S.

doi:10.1038/ng.970

articleNature GeneticsOct 16, 2011GREEN OA

Genome-wide association study identifies loci influencing concentrations of liver enzymes in plasma

JCJohn C. ChambersDGDiabetes Genetics Replication and Meta-analyses (DIAGRAM+) StudyWZWeihua Zhang JSJoban Sehmi MLMan Li

National Health Service · Imperial College Healthcare NHS Trust · +88 more institutions

PubMed

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Abstract

No abstract available for this paper.

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594

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Authors

137

JC
John C. ChambersCorresponding
National Health Service, Imperial College Healthcare NHS Trust, Ealing Hospital, Ealing Hospital NHS Trust, Imperial College London
DG
Diabetes Genetics Replication and Meta-analyses (DIAGRAM+) Study
Ealing Hospital, Ealing Hospital NHS Trust, Imperial College London
WZ
Weihua Zhang
Ealing Hospital, Hammersmith Hospital, Ealing Hospital NHS Trust, Imperial College London
JS
Joban Sehmi
Ealing Hospital, Hammersmith Hospital, Royal Brompton Hospital, Ealing Hospital NHS Trust, Imperial College London
ML
Man Li
Royal Brompton Hospital, Institute of Structural and Molecular Biology, Imperial College London

Topics & keywords

Topics

Keywords

Biology
Candidate gene
Genome-wide association study
Genetics
Gene
Genetic association
KEGG
Single-nucleotide polymorphism

UN Sustainable Development Goals

Good health and well-being

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