Experimental Models of Inflammatory Bowel Diseases
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Abstract
The understanding of the intestinal inflammation occurring in the inflammatory bowel diseases (IBD) has been immeasurably advanced by the development of the now numerous murine models of intestinal inflammation. The usefulness of this research tool in IBD studies has been enabled by our improved knowledge of mucosal immunity and thus our improved ability to interpret the complex responses of mice with various causes of colitis; in addition, it has been powered by the availability of models in which the mice have specific genetic and/or immunologic defects that can be related to the origin of the inflammation. Finally, and more recently, it has been enhanced by our newly acquired ability to define the…
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704
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Authors
3Topics & keywords
Topics
Keywords
- Inflammation
- Inflammatory bowel disease
- Inflammatory Bowel Diseases
- Colitis
- Medicine
- Microbiome
- Immunology
- Pathogenesis
UN Sustainable Development Goals
- Good health and well-being
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