The Arabidopsis CDPK-SnRK Superfamily of Protein Kinases
Scripps Research Institute · Georgia Institute of Technology · +7 more institutions
Abstract
The CDPK-SnRK superfamily consists of seven types of serine-threonine protein kinases: calcium-dependent protein kinase (CDPKs), CDPK-related kinases (CRKs), phosphoenolpyruvate carboxylase kinases (PPCKs), PEP carboxylase kinase-related kinases (PEPRKs), calmodulin-dependent protein kinases (CaMKs), calcium and calmodulin-dependent protein kinases (CCaMKs), and SnRKs. Within this superfamily, individual isoforms and subfamilies contain distinct regulatory domains, subcellular targeting information, and substrate specificities. Our analysis of the Arabidopsis genome identified 34 CDPKs, eight CRKs, two PPCKs, two PEPRKs, and 38 SnRKs. No definitive examples were found for a CCaMK similar to those previously…
Citation impact
- FWCI
- 39.73
- Percentile
- 100%
- References
- 115
Authors
14- EMEstelle M. HrabakCorresponding
Scripps Research Institute, Georgia Institute of Technology, University of Wisconsin–Madison, University of Arizona, University of New Hampshire, San Diego Supercomputer Center, University of Bristol, University of Glasgow, University of California, Berkeley
- CWCatherine W. M. Chan
Scripps Research Institute, Georgia Institute of Technology, University of Wisconsin–Madison, University of Arizona, University of New Hampshire, San Diego Supercomputer Center, University of Bristol, University of Glasgow, University of California, Berkeley
- MGMichael Gribskov
Scripps Research Institute, Georgia Institute of Technology, University of Wisconsin–Madison, University of Arizona, University of New Hampshire, San Diego Supercomputer Center, University of Bristol, University of Glasgow, University of California, Berkeley
- JFJeffrey F. Harper
Scripps Research Institute, Georgia Institute of Technology, University of Wisconsin–Madison, University of Arizona, University of New Hampshire, San Diego Supercomputer Center, University of Bristol, University of Glasgow, University of California, Berkeley
- JHJung Ho Choi
Scripps Research Institute, Georgia Institute of Technology, University of Wisconsin–Madison, University of Arizona, University of New Hampshire, San Diego Supercomputer Center, University of Bristol, University of Glasgow, University of California, Berkeley
Topics & keywords
- Arabidopsis
- Kinase
- Biology
- Protein-fragment complementation assay
- Genetics
- Protein-Serine-Threonine Kinases
- Protein kinase A
- Cell biology
- Good health and well-being