The SIDER database of drugs and side effects
Max Planck Institute of Molecular Cell Biology and Genetics · Biobyte Solutions (Germany) · +4 more institutions
Abstract
Unwanted side effects of drugs are a burden on patients and a severe impediment in the development of new drugs. At the same time, adverse drug reactions (ADRs) recorded during clinical trials are an important source of human phenotypic data. It is therefore essential to combine data on drugs, targets and side effects into a more complete picture of the therapeutic mechanism of actions of drugs and the ways in which they cause adverse reactions. To this end, we have created the SIDER ('Side Effect Resource', http://sideeffects.embl.de) database of drugs and ADRs. The current release, SIDER 4, contains data on 1430 drugs, 5880 ADRs and 140 064 drug-ADR pairs, which is an increase of 40% compared to the previous…
Citation impact
- FWCI
- 73.41
- Percentile
- 100%
- References
- 18
Authors
4Topics & keywords
- Drug
- Side effect (computer science)
- Database
- Adverse effect
- Placebo
- False positive paradox
- Drug reaction
- Pharmacology