articleGutOct 25, 2012BRONZE OA

Classification of acute pancreatitis—2012: revision of the Atlanta classification and definitions by international consensus

Harvard University · Brigham and Women's Hospital · +8 more institutions

PubMed
Indexed incrossrefpubmed

Abstract

Methods

A web-based consultation was undertaken in 2007 to ensure wide participation of pancreatologists. After an initial meeting, the Working Group sent a draft document to 11 national and international pancreatic associations. This working draft was forwarded to all members. Revisions were made in response to comments, and the web-based consultation was repeated three times. The final consensus was reviewed, and only statements based on published evidence were retained.

Results

The revised classification of acute pancreatitis identified two phases of the disease: early and late. Severity is classified as mild, moderate or severe. Mild acute pancreatitis, the most common form, has no organ failure, local or systemic complications and usually resolves in the first week. Moderately severe acute pancreatitis is defined by the presence of transient organ failure, local complications or exacerbation of co-morbid disease. Severe acute pancreatitis is defined by persistent organ failure, that is, organ failure >48 h. Local complications are peripancreatic fluid collections, pancreatic and peripancreatic necrosis (sterile or infected), pseudocyst and walled-off necrosis (sterile or infected). We present a standardised template for reporting CT images.

Citation impact

6,936
total citations
FWCI
190.29
Percentile
100%
References
82
Citations per year

Authors

8

Topics & keywords

Keywords
  • Medicine
  • Acute pancreatitis
  • Consensus conference
  • Pancreatitis
  • Exacerbation
  • Intensive care medicine
  • Pancreatic pseudocyst
  • Disease
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