Fast transient networks in spontaneous human brain activity

Baker, Adam; Brookes, Matthew J.; Rezek, Iead; Smith, Stephen M.; Behrens, Timothy E.J.; Smith, Penny J Probert; Woolrich, Mark W.

doi:10.7554/elife.01867

articleeLifeMar 25, 2014GOLD OA

Fast transient networks in spontaneous human brain activity

ABAdam Baker MJMatthew J. Brookes IRIead Rezek SMStephen M. Smith TETimothy E.J. Behrens

University of Oxford · Wellcome Centre for Integrative Neuroimaging · +5 more institutions

PubMed

Indexed incrossrefdoajpubmed

Abstract

To provide an effective substrate for cognitive processes, functional brain networks should be able to reorganize and coordinate on a sub-second temporal scale. We used magnetoencephalography recordings of spontaneous activity to characterize whole-brain functional connectivity dynamics at high temporal resolution. Using a novel approach that identifies the points in time at which unique patterns of activity recur, we reveal transient (100-200 ms) brain states with spatial topographies similar to those of well-known resting state networks. By assessing temporal changes in the occurrence of these states, we demonstrate that within-network functional connectivity is underpinned by coordinated neuronal dynamics…

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635

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Topics & keywords

Topics

Keywords

Magnetoencephalography
Default mode network
Task-positive network
Neuroscience
Network dynamics
Dynamic functional connectivity
Computer science
Human brain

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