Neurohumoral Features of Myocardial Stunning Due to Sudden Emotional Stress

Wittstein, Ilan S.; Thiemann, David R.; Lima, João A.C.; Baughman, Kenneth L.; Schulman, Steven P.; Gerstenblith, Gary; Wu, Kathérine C.; Rade, Jeffrey J.; Bivalacqua, Trinity J.; Champion, Hunter C.

doi:10.1056/nejmoa043046

articleNew England Journal of MedicineFeb 9, 2005BRONZE OA

Neurohumoral Features of Myocardial Stunning Due to Sudden Emotional Stress

ISIlan S. Wittstein DRDavid R. Thiemann JAJoão A.C. Lima KLKenneth L. Baughman SPSteven P. Schulman

Johns Hopkins University · Johns Hopkins Medicine · +1 more institution

PubMed

Indexed incrossrefpubmed

Abstract

Background

Reversible left ventricular dysfunction precipitated by emotional stress has been reported, but the mechanism remains unknown.

Methods

We evaluated 19 patients who presented with left ventricular dysfunction after sudden emotional stress. All patients underwent coronary angiography and serial echocardiography; five underwent endomyocardial biopsy. Plasma catecholamine levels in 13 patients with stress-related myocardial dysfunction were compared with those in 7 patients with Killip class III myocardial infarction.

Citation impact

3,103

total citations

FWCI: 110.44
Percentile: 100%
References: 38

Citations per year

Authors

10

Topics & keywords

Topics

Keywords

Interquartile range
Medicine
Cardiology
Myocardial infarction
Internal medicine
Ejection fraction
Cardiomyopathy
Killip class

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