articleNucleic Acids ResearchJun 8, 2012GOLD OA

RobiNA: a user-friendly, integrated software solution for RNA-Seq-based transcriptomics

Max Planck Society · Max Planck Institute of Molecular Plant Physiology

PubMed
Indexed incrossrefdoajpubmed

Abstract

Recent rapid advances in next generation RNA sequencing (RNA-Seq)-based provide researchers with unprecedentedly large data sets and open new perspectives in transcriptomics. Furthermore, RNA-Seq-based transcript profiling can be applied to non-model and newly discovered organisms because it does not require a predefined measuring platform (like e.g. microarrays). However, these novel technologies pose new challenges: the raw data need to be rigorously quality checked and filtered prior to analysis, and proper statistical methods have to be applied to extract biologically relevant information. Given the sheer volume of data, this is no trivial task and requires a combination of considerable technical resources…

No related works found for this paper.

Funding