RobiNA: a user-friendly, integrated software solution for RNA-Seq-based transcriptomics
Max Planck Society · Max Planck Institute of Molecular Plant Physiology
Abstract
Recent rapid advances in next generation RNA sequencing (RNA-Seq)-based provide researchers with unprecedentedly large data sets and open new perspectives in transcriptomics. Furthermore, RNA-Seq-based transcript profiling can be applied to non-model and newly discovered organisms because it does not require a predefined measuring platform (like e.g. microarrays). However, these novel technologies pose new challenges: the raw data need to be rigorously quality checked and filtered prior to analysis, and proper statistical methods have to be applied to extract biologically relevant information. Given the sheer volume of data, this is no trivial task and requires a combination of considerable technical resources…
Citation impact
- FWCI
- 45.68
- Percentile
- 100%
- References
- 38
Authors
7- MLMarc LohseCorresponding
Max Planck Society, Max Planck Institute of Molecular Plant Physiology
- ABAnthony Bolger
Max Planck Society, Max Planck Institute of Molecular Plant Physiology
- ANAxel Nagel
Max Planck Society, Max Planck Institute of Molecular Plant Physiology
- ARAlisdair R. Fernie
Max Planck Society, Max Planck Institute of Molecular Plant Physiology
- JEJohn E. Lunn
Max Planck Society, Max Planck Institute of Molecular Plant Physiology
Topics & keywords
- Bioconductor
- Software
- RNA-Seq
- OS X
- Graphical user interface
- Computer science
- User Friendly
- Profiling (computer programming)
- Industry, innovation and infrastructure