Amygdala–frontal connectivity during emotion regulation
University of Chicago · Brain Research Foundation · +1 more institution
Abstract
Successful control of affect partly depends on the capacity to modulate negative emotional responses through the use of cognitive strategies (i.e., reappraisal). Recent studies suggest the involvement of frontal cortical regions in the modulation of amygdala reactivity and the mediation of effective emotion regulation. However, within-subject inter-regional connectivity between amygdala and prefrontal cortex in the context of affect regulation is unknown. Here, using psychophysiological interaction analyses of functional magnetic resonance imaging data, we show that activity in specific areas of the frontal cortex (dorsolateral, dorsal medial, anterior cingulate, orbital) covaries with amygdala activity and…
Citation impact
- FWCI
- 9.46
- Percentile
- 100%
- References
- 94
Authors
5Topics & keywords
- Amygdala
- Psychology
- Neuroscience
- Functional magnetic resonance imaging
- Anterior cingulate cortex
- Prefrontal cortex
- Orbitofrontal cortex
- Context (archaeology)